She was diagnosed with terminal lung cancer earlier this year, and had chosen to die with Voluntary Assisted Dying (VAD).
Worthington chronicled her end-of-life journey for a documentary following a lung and breast cancer diagnosis in July 2024.
WA legalised VAD in July 2021 and Worthington was a supporter of the legislative change.
“I do want to leave the impact that voluntary assisted dying can be one of the most beautiful experiences that you could ever have, but more importantly, for your family,” Worthington told ABC News in September.
“No-one wants to die in pain. I don’t want to die in pain.”
The philanthropist was a fierce champion of West Australians suffering from breast cancer.
Worthington founded Breast Cancer Care WA in 2000 after experience with chronic breast disease and a mastectomy at age 34.
The charity since raised over $40 million for Western Australians diagnosed with breast cancer and their families.
She received an Order of Australia Medal in 1998 and was crowned Western Australian of the Year in 2015.
Breast Cancer Care WA issued a statement following Worthington’s death and acknowledged her incredible legacy of charity work.
“As we honour Ros’s memory, we celebrate the wonderful legacy she leaves behind— one of hope and unwavering commitment to making a difference,” the statement read.
“We will always remember Ros as a powerhouse of compassion and her influence will continue through our support services at BCCWA.”